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Mechanical regulation of gene expression associated with metastatic aggression in bone-seeking breast cancer cells.

Mechanical regulation of gene expression associated with metastatic aggression in bone-seeking breast cancer cells.
与寻骨乳腺癌细胞转移侵袭相关的基因表达的机械调节。
批准号：
367260
负责人：
Mei Junyi
金额：
$1.27万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-12-01 至 2017-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=367260&lang=en
关键词：
Bone Bone Stroma Breast Cancer Fluid Flow Stimuli Gene Expression Mechanical Loading Metastasis Osteocyte Perivascular Niche Tumor Agression

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Breast cancer relapses can occur decades after successful treatment. When relapses involve cancer cells that have traveled through the bloodstream to settle in bone, these new tumors, termed metastases, become incurable. Bone metastases are responsible fo
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