Grant for Exploratory Research: Field Cycling Electron Nuclear Double Resonance Studies

阿尔文教授Kwiram得到小额赠款的支持， 物理化学实验探究 计划调查执行零场的潜力 电子自旋共振（ESR）谱。 如果他成功了， 这项新技术将提供许多独特的优势， 研究结构的传统ESR方法， 有机自由基的动力学 零场核磁共振（NMR）技术具有 已经有一段时间了。 主要优势在于 传统的核磁共振，这是由于增加灵敏度， 测量小型核四极耦合的能力 常数以及自旋半核的非常小的分裂。 Kwiram计划采用快速电子开关技术， 实现ESR场循环。 电子开关是 必要的，而不是机械的方法在零 场核磁共振光谱，因为弛豫时间短得多， 在典型的ESR实验中遇到的时间。 如果成功， 所得到的零场ESR应该具有灵敏度 比传统方法提高约两个数量级， 大小 这种增加的灵敏度将打开 可能进行一些新的实验， 基质分离物种和生物分子。

Professor Alvin L. Kwiram is supported by a Small Grant for Exploratory Research from the Experimental Physical Chemistry Program to investigate the potential for performing zero field electron spin resonance (ESR) spectroscopy. If he succeeds, this new technique will offer many unique advantages over conventional ESR methodologies for studying structure and dynamics of organic free radicals. Zero field nuclear magnetic resonance (NMR) techniques have been known for some time now. The primary advantage over conventional NMR, which arises from increased sensitivity, is the capability of measuring small nuclear quadrupole coupling constants as well as very small splittings of spin half nuclei. Kwiram plans to employ rapid electronic switching techniques to implement field cycling for ESR. Electronic switching is necessary rather than the mechanical methods employed in zero field NMR spectroscopy, because of the much shorter relaxation times encountered in typical ESR experiments. If successful, the resulting zero field ESR should have a sensitivity enhancement over conventional methods of about two orders of magnitude. This increased sensitivity will open up the possibility of a number of new experiments involving studies of matrix isolated species and biological molecules.