Chemistry of Organosulfur Compounds

有机硫化合物化学

• 批准号: 9015849
• 负责人: Fillmore Freeman
• 金额: $ 25.8万
• 依托单位: University of California-Irvine
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-08-15 至 1995-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9015849&HistoricalAwards=false
• 关键词: Chemistry; Organosulfur; Compounds

The focus of this project in the Organic Chemical Dynamics Program is the chemistry of organosulfur compounds. This family of compounds includes a number of substances of vital importance in biological systems, important starting materials and intermediates in synthetic organic chemistry, and several compounds which play important roles in environmental chemistry. The project will emphasize reaction intermediates and unstable species which are involved in the synthesis and reaction mechanisms of selected organic compounds of sulfur and other chalcogens. One phase of the project will be the study of the chemistry of imidazole-2-chalcogenones (-2-thiones; -2-selenones; -2-tellurones). This will include a kinetic and mechanistic study of charge transfer complex formation with halogens and cyanogen halides, the preparation and chemistry of imidazolyl sulfines, selenines and tellurines. In another aspect of the project, the oxidation of disulfides, trisulfides, thioozonides, sulfenic acids, and sulfinic acids will be investigated. The mechanisms and products from the reactions of sulfinyl halides with light, heat, amides, sulfenic acids, and sulfines will be studied. Molecular orbital calculations will be performed for many of the reaction intermediates and products.

有机化学动力学计划的这个项目的重点是有机硫化合物的化学。这一类化合物包括一些在生物系统中至关重要的物质，合成有机化学中的重要起始原料和中间体，以及在环境化学中发挥重要作用的几种化合物。该项目将侧重于硫磺和其他硫族有机化合物的合成和反应机理中涉及的反应中间体和不稳定物种。该项目的一个阶段将是研究咪唑-2-硫酮(-2-硫酮；-2-硒酮；-2-碲酮)的化学。这将包括与卤素和卤化氰形成电荷转移络合物的动力学和机理研究，咪唑基亚硫醚、硒和碲的制备和化学。在该项目的另一个方面，将研究二硫化物、三硫化物、硫代臭氧、磺酸和亚磺酸的氧化。本课程将研究卤化亚磺与光、热、酰胺、磺酸和亚硫醚反应的机理和产物。将对许多反应中间体和产物进行分子轨道计算。