U.S-France Joint Seminar: Multiple Sigma and PCP Receptor Ligands: Mechanisms for Neural Modulation and Protection, Montpellier, France, September 1991

这项奖金将支持美国参加将于1991年9月在法国蒙彼利埃举行的关于“多重西格玛和PCP受体配体：神经调节和保护机制”的美法联合研讨会。美国和法国的组织者是：密歇根大学药学系的Edward Domino博士和法国蒙彼利埃国立化学高等学院的Jean-Marc Kamenka博士。研讨会将涵盖sigma和PCP受体配体在化学、生物化学、分子生物学、神经行为科学、精神药理学和毒理学中的应用。它们与不同神经递质或调节剂的相互作用将被更新，并将描述对特定sigma和PCP受体激动剂和拮抗剂的研究。PCP及其衍生物是目前生物学许多方面重要的分子探针，也被认为是抗精神病药、抗惊厥药和神经保护剂等新的治疗方法。本次研讨会将汇集这一快速发展的研究领域的领先专家，并将提供宝贵的互动机会。讨论会的结果将会出版，预计将在科学界广泛传播。

This award will support US participation in a US-France joint seminar on the topic of "Multiple Sigma and PCP Receptor Ligands: Mechanisms for Neural Modulation and Protection?", to be held in Montpellier, France, in September 1991. The US and French organizers are: Dr. Edward Domino, Department of Pharmacology, University of Michigan, and Dr. Jean-Marc Kamenka, Ecole Nationale Superieure de Chimie, Montpellier, France. The seminar will cover the use of sigma and PCP receptor ligands in chemistry, biochemistry, molecular biology, neurobehavioral sciences, psychopharmacology and toxicology. Their interaction with different neurotransmitters or modulators will be updated and the search for specific sigma and PCP receptor agonists and antagonists will be described. PCP and its derivatives are currently important molecular probes in many aspects of biology and are also being considered as novel therapy as antipsychotic, anticonvulsant and neural protective agents. This seminar will bring together leading experts in this rapidly moving field of study and will provide an opportunity for valuable interactions. Results of the seminar will be published and are expected to be disseminated widely in the scientific community.