Development of an Object-Oriented Approach for Managing Genomic Mapping Data

开发更有效的储存基因组的方法- 相关信息输入计算机系统和软件应用程序 数据分析是人类基因组的重要方面 目前正在进行的其他基因组计划。 的 需要开发更好的计算机辅助信息库 基因组相关的研究正在产生大量的 无法充分利用现有数据进行建模的数据 关系数据库技术。 这个项目将测试假设，面向对象 在基因组建模方面， 相关数据。 此外，该项目还将测试 面向对象的方法提供了更好的界面开发 环境，关系的方法。 E.大肠杆菌基因组数据将用于开发一个面向对象的 包含基因图谱、物理图谱、DNA 序列和转座子插入位点。 对于原型设计， 最新版本的第二代面向对象 数据库，来自Ontologic公司的ONTOS，将用于

The development of more efficient methods for storing genome- related information into computer systems and software applications for data analysis are important aspects of the Human Genome initiative and of other genome projects currently underway. The need to develop improved computer-assisted information repositories is obvious; genome-related research is producing massive amounts of data that cannot be adequately modelled using currently relational database technologies. This project will test the hypothesis that the object-oriented approach outperforms the relational approach for modelling genome- related data. In addition, this project will test whether the object-oriented approach provides a better interface development environment that the relational approach. E. coli genome data will be used to develop an object-oriented prototype database that contains genetic maps, physical maps, DNA sequences, and transposon insertion sites. For prototyping, the most recent version of a second generation object-oriented database, ONTOS from Ontologic, Inc., will be used.