The Identification of the Amino Acids on Platelet Factor 4 That Bind Pathogenic Antibodies in Heparin-Induced Thrombocytopenia
The Identification of the Amino Acids on Platelet Factor 4 That Bind Pathogenic Antibodies in Heparin-Induced Thrombocytopenia
批准号:
383339
负责人:
Huynh Angela
金额:
$7.65万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-10-01 至 2020-10-01
中文摘要
至少30%的入院患者会接触到常见的抗凝剂肝素。这些患者中有1-3%发生肝素诱导的血小板减少症(HIT):一种可导致截肢、中风和死亡的药物不良反应。击中
英文摘要
At least 30% of patients admitted into the hospital will be exposed to the common anticoagulant, heparin. 1-3% of these patients develop heparin-induced thrombocytopenia (HIT): an adverse drug reaction that can lead to amputations, strokes, and death. HIT
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会议论文
Pathogenic Antibodies in Heparin-induced Thrombocytopenia Specifically Target an Immunodominant Region on Platelet Factor 4
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批准号:411554
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项目类别:
-
资助金额:$0.07万
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财政年份:2019
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负责人:Huynh Angela
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依托单位:
海外基金