Conducting Polymers for Iontophoretic Self-Administration Drug Delivery Devices

这项基础研究是为了研究使用导电聚合物进行药物电子控制释放的可行性。该提议的新奇之处在于使用了光聚合，而不是更传统的电化学聚合过程。这种新方法允许聚合物薄膜的三维生长，并有望促进药物进入聚合物基质。由于聚合物是导电的，电信号最终可能用于控制药物的释放速度。第一阶段的研究将集中在光聚合过程的研究上。如果成功，这项研究可能会对长期治疗中的药物输送方式产生重大影响。

This basic study is to examine the feasibility of using conducting polymers for the electronically controlled release of drugs. The novelty of the proposal is in the use of a photo-polymerization rather than the more conventional electrochemical polymerization process. The new method allows the three-dimensional growth of polymer films, and is expected to facilitate the incorporation of drugs into the polymer matrix. Since the polymers are conductive, electrical signals may eventually be used for controlling the rate of drug release. Phase 1 research will concentrate on the study of the photo-polymerization process. If successful, this research could have a substantial impact on the way medicine is delivered in long-term therapy.