Conducting Polymers for Iontophoretic Self-Administration Drug Delivery Devices

用于离子电渗自我给药给药装置的导电聚合物

• 批准号: 9060319
• 负责人: Oliver Murphy
• 金额: $ 5万
• 依托单位: Lynntech, Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-01-01 至 1991-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9060319&HistoricalAwards=false
• 关键词: Conducting; Polymers; Iontophoretic; Self; Administration

This basic study is to examine the feasibility of using conducting polymers for the electronically controlled release of drugs. The novelty of the proposal is in the use of a photo-polymerization rather than the more conventional electrochemical polymerization process. The new method allows the three-dimensional growth of polymer films, and is expected to facilitate the incorporation of drugs into the polymer matrix. Since the polymers are conductive, electrical signals may eventually be used for controlling the rate of drug release. Phase 1 research will concentrate on the study of the photo-polymerization process. If successful, this research could have a substantial impact on the way medicine is delivered in long-term therapy.

本基础研究旨在探讨导电聚合物用于药物电子控制释放的可行性。该提议的新颖之处在于使用光聚合而不是更传统的电化学聚合过程。新方法允许聚合物薄膜的三维生长，并有望促进药物进入聚合物基质。由于聚合物具有导电性，电信号最终可用于控制药物释放速率。第一阶段的研究将集中于光聚合过程的研究。如果成功，这项研究可能会对长期治疗中的药物输送方式产生重大影响。