Identification of novel intestinal stem cell targets in colitis and cancer

结肠炎和癌症中新型肠道干细胞靶标的鉴定

• 批准号: 394044
• 负责人: Asfaha Samuel
• 金额: $ 13.11万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Salary Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-10-01 至 2021-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=394044&lang=en
• 关键词: Colitis; Colon Cancer; Stem Cells

In rapidly dividing tissues such as the intestine or colon, only tissue stem cells display the longevity and ability to regenerate all cell types. Unfortunately, this unique longevity of stem cells is also what predisposes them to acquire mutations that l

在快速分裂的组织中，如肠或结肠，只有组织干细胞显示出寿命和再生所有类型细胞的能力。不幸的是，干细胞的这种独特的长寿也是使它们容易获得突变的原因，L