Regulatory Determinants of JH-esterase Activity Polymorphism

JH-酯酶活性多态性的调控决定因素

• 批准号: 9105257
• 负责人: Anthony Zera
• 金额: $ 13.81万
• 依托单位: University of Nebraska-Lincoln
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-10-01 至 1995-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9105257&HistoricalAwards=false
• 关键词: Regulatory; Determinants; JH; esterase; Activity

The basic goal of this proposal is to determine the physiological mechanisms that cause individuals of the cricket Gryllus rubens to produce either a high or low amount of the key enzyme juvenile hormone esterase. High enzyme concentration causes individuals to develop into a long-winged, dispersing form while low enzyme concentration causes the development of short-winged, flightless adults. This research will clarify the mechanisms by which hormones regulate important developmental processes in insects. Since amount of juvenile hormone esterase produced is genetically determined, this study will be especially important in identifying genetic aspects of the hormonal regulation of development. In addition, these high and low-enzyme genotypes of G. rubens are found naturally in the field. Thus, this study will also identify how evolution is altering development to produce a new phenotype (short-winged, non-flying form in this case). This is currently one of the most important but poorly understood aspects of evolution. Last, by providing information on the regulation of development, this study will provide important background information for applied studies that attempt to disrupt development to control insect populations. //

这项建议的基本目标是确定生理 使蟋蟀蟋蟀个体 产生或高或低数量的关键酶幼 激素酯酶 高酶浓度导致个体 发展成长翅膀，分散的形式，而低酶 浓度导致短翅，不会飞的发展 成年人了 这项研究将阐明 激素调节昆虫重要的发育过程。 由于保幼激素酯酶的产生量是遗传的， 确定，这项研究将是特别重要的，在确定 激素调节发育的遗传方面。 在 此外，G.鲁本斯群岛 在野外自然发现。 因此，本研究还将确定 进化是如何改变发育产生新的表型 （短翅，在这种情况下不飞行的形式）。 这是目前 其中最重要但知之甚少的一个方面， 进化 最后，通过提供关于 发展，这项研究将提供重要的背景 用于试图破坏发展的应用研究的信息 来控制昆虫的数量//