Peripheral and central chemoreceptor reflex regulation of sympathetic activity in heart failure patients

心力衰竭患者交感神经活动的外周和中枢化学感受器反射调节

• 批准号: 397530
• 负责人: Keir Daniel A
• 金额: $ 9.83万
• 依托单位: Toronto General Hospital
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-11-01 至 2021-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=397530&lang=en
• 关键词: Autonomic Reflexes; Central Chemoreceptor Reflexes; Heart Failure; Human Research; Microneurography; Peripheral Chemoreceptor Reflexes; Ventilation

When the heart fails to pump normally, the brain releases into the bloodstream increased amounts of a chemical called noradrenaline. Noradrenaline increases heart rate, causes the kidneys to pass less salt and water and constricts blood vessels. At first,

当心脏无法正常泵血时，大脑会向血液中释放大量称为去甲肾上腺素的化学物质。去甲肾上腺素会增加心率，导致肾脏排出较少的盐和水，并收缩血管。起初，