Do bias signaling of the apelinergic receptor can improve the treatment of acute cardiovascular dysfunction and injury related to septic shock?
Do bias signaling of the apelinergic receptor can improve the treatment of acute cardiovascular dysfunction and injury related to septic shock?
批准号:
396834
负责人:
Coquerel David
金额:
$6.56万
依托单位:
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-11-01 至 2020-11-01
中文摘要
血流动力学和器官/组织灌注的紧急稳定是脓毒性休克治疗的基石,严重影响心肌功能和血管树。长期以来,与液体复苏相结合的儿茶酚胺治疗一直是
英文摘要
Urgent stabilization of hemodynamics and organ/tissue perfusion is a cornerstone in septic shock treatment, which seriously affects the myocardial function and the vascular tree. Catecholamines treatment, in concert with fluid resuscitation, has long been
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Gi/Adenylyl Cyclase/cAMP signaling pathway coupling APJ receptor is a negative feedback of the inotropic response of apelin-13: impact of biased ligands.
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批准号:368308
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项目类别:
-
资助金额:$0.07万
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财政年份:2017
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负责人:Coquerel David
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依托单位:
Caractérisation de nouveaux analogues de l'Apeline-13 modifiés en C-terminal sur la fonction cardiaque et étude de leurs impacts cardioprotecteurs en condition d'agression septique.
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批准号:331837
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项目类别:
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资助金额:$0.09万
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财政年份:2015
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负责人:Coquerel David
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依托单位:
海外基金