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Combatting the burden of drug-related toxicities in childhood cancer through genomics-based interventions

Combatting the burden of drug-related toxicities in childhood cancer through genomics-based interventions
通过基于基因组学的干预措施来应对儿童癌症中药物相关毒性的负担
批准号：
396835
负责人：
Loucks Catrina M
金额：
$9.83万
依托单位：
BC Children's Hospital Research Institute
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-11-01 至 2021-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=396835&lang=en
关键词：
Childhood Cancer Drug-Related Toxicities Methotrexate Mucositis Pharmacogenomics

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英文摘要
While the 5-year survival rates for children with cancer continue to improve, the major problem of drug-related side effects remains. For example, the cancer therapy drug, methotrexate, can save a child's life, but it can also lead to mucositis, a painful
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