Intravenous Coronary Angiography Utilizing K-Emission and Bremsstrahlung X-Rays Produced by Electron Bombardment

目前的冠状动脉造影技术需要在冠状动脉内注射造影剂；理论分析表明，通过获取两种不同能量的x射线之间的差异，并使用适当的造影剂和信号处理技术，冠状动脉造影可以通过静脉注射获得。这项提议是为了测试这种方法的可行性，而不需要开发能够处理必要的高电子电流的x射线管。提出的方法是使用低电极电流（来自布鲁克海文Dynamitron电子加速器）生成幻影图像，并使用平均来补偿低电流。如果初步结果是有希望的，后续工作是成功的，将产生更安全，更低成本的血管造影技术。

The current technique of coronary angiography requires the injection of a contrast agent into the coronary artery; this procedure is expensive and potentially hazardous theoretical analysis shows that by taking the difference between X-rays at two different energies, and by using an appropriate contrast agent and signal processing techniques, coronary angiograms can be obtained using intravenous injection. This proposal is to test the feasibility of the approach without the development of an X-ray tube that is able to handle the necessary high electron currents. The proposed approach is to generate images of phantoms using low electrode currents (form the Brookhaven Dynamitron electron accelerator) and using averaging to compensate for the low current. If the preliminary results are promising, and follow-up work is successful, a safer and lower cost angiographic technology will result.