Microbiome regulation of beta cell autoimmunity and diabetes

β细胞自身免疫和糖尿病的微生物组调节

• 批准号: 404242
• 负责人: Danska Jayne S
• 金额: $ 1.82万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-11-01 至 2019-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=404242&lang=en
• 关键词: Flow Cytometry; Human Prospective Studies; Immunology; Metabolomics; Microbiome; Mouse Models; Multi/Variate Statistical Analysis; Type 1 Diabetes

The last 50 years have seen a dramatic rise in frequency of autoimmune diseases in the developed world. These include autoimmune or "type 1"diabetes that results from immune destruction of the insulin producing cells in the pancreas leaving the patient

在过去的50年里，自身免疫性疾病在发达国家的发病率急剧上升。其中包括自身免疫或“1型”糖尿病，这是由于胰腺中产生胰岛素的细胞被免疫破坏而导致的