Olfactory Mixture Interactions: Mechanisms and Effects

嗅觉混合物相互作用：机制和效果

• 批准号: 9109783
• 负责人: Charles Derby
• 金额: $ 24.96万
• 依托单位: Georgia State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-03-15 至 1996-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9109783&HistoricalAwards=false
• 关键词: Olfactory; Mixture; Interactions; Mechanisms; Effects

The major objective of this research is to understand the molecular, cellular and systems-level mechanisms responsible for the detection and discrimination of odorant mixtures and their components. This includes gaining an understanding of the effects of mixtures interactions on coding in the nervous system as well as the behavioral discrimination of odors and intensity. Experiments are conducted using the spiny lobster and a set of 7 odorant to examine the effects of mixture interactions on nerve cell activity and behavioral responses using conditioning techniques to examine discrimination of odorant. These studies will contribute to a better understanding of the events that underlie the perception of odorant and how a relatively simple nervous system encodes this sensory information and uses it to control behavior to chemical substances.

本研究的主要目的是了解 分子、细胞和系统水平的机制， 气味混合物的检测和辨别及其 件. 这包括了解 混合物相互作用对神经系统编码的影响 以及对气味和强度的行为辨别。 实验使用多刺龙虾和一组7只 气味剂来检查混合物相互作用对神经的影响 细胞活性和行为反应 技术来检查气味的辨别。 这些研究 将有助于更好地了解 气味感知的基础，以及相对简单的 神经系统编码这种感觉信息，并利用它来 控制对化学物质的行为。