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Role of ATP-P2X7 axis in pathogenesis of ventilator induced lung injury

Role of ATP-P2X7 axis in pathogenesis of ventilator induced lung injury
ATP-P2X7 轴在呼吸机所致肺损伤发病机制中的作用
批准号：
400845
负责人：
Grygorczyk Ryszard
金额：
$28.65万
依托单位：
Centre hospitalier de l'Universit de Montral (CHUM)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-03-01 至 2022-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=400845&lang=en
关键词：
Acute Lung Injury Acute Respiratory Distress Syndrom Alveolar Cells Bioluminescence Atp Imaging Ex Vivo Lung Lung Airspaces Lung Edema And Inflammation Purinergic Signaling Stress-Sensitive Atp Release Ventilator Induced Lung Injury

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中文摘要
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英文摘要
Mechanical ventilation (MV) is indispensable for the survival of critically ill patients, such as those with respiratory failure. However, improperly delivered, can aggravate or cause acute lung injury (ALI) and acute respiratory distress syndrome (ARDS).
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Mechanosensitive ATP release in the lungs