U.S.-Japan Seminar: Gene Regulation and Expression in Mitochondrial Disease and the Aging Process/December 1992/ Honolulu, Hawaii

该奖项将支持10名美国科学家参加美日关于线粒体疾病和衰老过程中的基因调控和表达的研讨会。该研讨会将于1992年12月7日至12日在夏威夷檀香山举行，由俄勒冈大学分子生物学研究所Roderick Capaldi教授和名古屋大学生物医学化学系Takayuki Ozawa博士共同组织。研讨会将集中讨论线粒体生物发生基础研究的最新进展，将研究氧化磷酸化基本过程的科学家的兴趣与研究各种疾病和衰老过程中线粒体功能障碍的科学家的兴趣结合起来。除了美国和日本的科学家外，来自澳大利亚的研究人员也将参加这次研讨会。这次讨论会是继1987年12月成功举行的讨论会之后举行的。研讨会的主题是：线粒体DNA的结构和复制、线粒体分子生物学的调控、线粒体酶复合物的生物化学、生物能量学及其与线粒体疾病的关系、与疾病相关的线粒体突变的性质、线粒体和衰老过程以及线粒体疾病的治疗。研讨会的目标是鼓励分享专门知识，这可能导致在这一重要研究领域的合作。

This award will support the participation of ten U.S. scientists in a U.S.-Japan Seminar on Gene Regulation and Expression in Mitochondrial Disease and the Aging Process. The seminar, which will be held December 7-12, 1992, in Honolulu, Hawaii, is being co-organized by Professor Roderick Capaldi, Institute of Molecular Biology, University of Oregon, and Dr. Takayuki Ozawa, Department of Biomedical Chemistry, Nagoya University. The seminar will focus on the latest developments in basic research on mitochondrial biogenesis, combining the interests of scientists who study the basic process of oxidative phosphorylation with those who study mitochondrial dysfunction in a wide variety of diseases and in the aging process. In addition to U.S. and Japanese scientists, the seminar will include researchers from Australia. This seminar follows a successful seminar in December 1987. The seminar topics are: structure and replication of mitochondrial DNA, regulation of mitochondrial molecular biology, biochemistry of mitochondrial enzyme complexes, bioenergetics and relationship to mitochondrial disease, nature of mitochondrial mutations associated with disease, mitochondria and the aging process, and treatment of mitochondrial diseases. The goal of the seminar is to encourage the sharing of expertise, which could lead to collaboration in this important area of research.