Ring Mediated Interaction of Non-Rigid Moeities

在这个项目中的物理化学计划的 化学部，李汉教授。蒙大拿州立大学 大学将研究电子状态的影响， 分子的非刚性部分之间的相互作用。 具体而言，甲基和胺的相互作用将被检查为 π电子系统分子中距离的函数 使用应用于样品的各种光谱技术 在超音速喷射膨胀中制备。 了解 电子状态对构象变化的影响是 预期的结果。 %%% 分子的大幅度低频运动影响 构象偏好和反应特异性 这些分子。 例如，了解构象 从基础研究中获得的试剂分子， 一个小得多的相关物种的结构允许一个 研究人员设计了一个合成路线，为一大类 聚醚类抗生素 详细了解什么 决定了构象的偏好， 分子环境和电子状态也是关键， 了解生物活动。 本项目旨在 收集几种类型的构象信息 分子系统

In this project in the Physical Chemistry Program of the Chemistry Division, Professor Lee H. Spangler of Montana State University will study the effect of the electronic state of a molecule on interactions between its non-rigid parts. Specifically, methyl and amine interactions will be examined as a function of distance in molecules with pi-electron systems using various spectroscopic techniques applied to samples prepared in a supersonic jet expansion. An understanding of the influence of electronic state on conformational changes is expected to result. %%% The large amplitude, low frequency motions of molecules affect the conformational preferences and reaction specificity of those molecules. For example, knowledge of the conformation of a reagent molecule obtained from the fundamental study of the structure of a much smaller related species allowed one researcher to devise a synthetic route for a large class of polyether antibiotics. A detailed understanding of what determines conformational preferences as a function of molecular environment and electronic state is also key to understanding biological activity. The current project aims at gathering conformational information in several types of molecular systems.