FT-NMR for Improved Undergraduate Instruction and Research

FT-NMR 用于改进本科教学和研究

• 批准号: 9151147
• 负责人: William Wood
• 金额: $ 8.85万
• 依托单位: Humboldt State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-04-01 至 1993-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9151147&HistoricalAwards=false
• 关键词: FT; NMR; Improved; Undergraduate; Instruction

A 200 MHz NMR spectrometer with 1H, 13C and 2D capability will be acquired to enhance undergraduate research and instruction. A Varian Gemini 200 Spectrometer will replace an obsolete and frequently inoperable 60 MHz CW instrument. Several novel experiments for the FT-NMR instrument will extend beyond 1H NMR in the organic chemistry courses. It will be used intensively in organic chemistry instruction and will also be used in laboratory courses in analytical chemistry, biochemistry, inorganic chemistry and instrumental methods. A number of current senior projects that cannot be done with the present instrument can be completed on a sensitive high field NMR. These include structural studies on an organochlorine compound from a Clitocybe mushroom, characterization of a sesquiterpene that smells like cedar from a Hygrophorous mushroom, characterization of a highly reactive aminobenzoquinone from a Lepiota mushroom, and further structural studies on buzonamine, a novel epoxy-alkaloid from the millipede Buzonium crassipes. The grantee is matching this award from non-Federal sources.

将获得一台具有1H， 13C和2D能力的200 MHz核磁共振光谱仪，以加强本科生的研究和教学。瓦里安双子座200光谱仪将取代过时且经常无法操作的60兆赫连续波仪器。在有机化学课程中，FT-NMR仪器的几个新实验将扩展到1H NMR之外。它将在有机化学教学中大量使用，也将在分析化学、生物化学、无机化学和仪器方法的实验课程中使用。一些目前不能用现有仪器完成的高级项目可以在一个敏感的高场核磁共振上完成。这些研究包括对一种Clitocybe蘑菇中有机氯化合物的结构研究，对一种吸湿蘑菇中闻起来像雪松的倍半萜的表征，对一种Lepiota蘑菇中高活性氨基苯醌的表征，以及对一种来自千足虫Buzonium crassipes的新型环氧生物碱buzonamine的进一步结构研究。受助人将从非联邦来源获得相应的奖励。