Presidential Young Investigator Award

精子成熟和糖苷酶。精子使精子有效受精的能力是在通过附睾的过程中获得的。霍尔博士提出了一种假说，即精子是通过修改表面膜，特别是修改细胞表面的碳水化合物分子来“激活”的。他提出，附睾会分泌改变表面碳水化合物的酶。他计划详细研究这些酶及其分泌。可以想象，这项基础研究可能会导致开发有效的男性避孕药。

Sperm maturation and glycosidic enzymes. The capacity of sperm to effectively fertilize an overm is acquired during passage through the epididymis. Dr. Hall has developed a hypothesis that sperm are "activated" by modification of surface membrane, specifically, modification of carbohydrate molecules on the cell surface. He proposes that the epididymis secretes enzymes that alter surface carbohydrates. He plans to study these enzymes and their secretion in detail. It is conceivable that this basic research could lead to development of effective male contraceptives.//