Interplay of Neuroinflammation and Synaptic Plasticity in Neurodegeneration
Interplay of Neuroinflammation and Synaptic Plasticity in Neurodegeneration
批准号:
419278
负责人:
Jackson Michael F
金额:
$84.43万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-03-01 至 2025-03-01
中文摘要
小胶质细胞是一类大脑免疫细胞,在神经炎症中发挥重要作用,神经炎症是一种为抵御毒素和病原体而启动的保护性反应。然而,在阿尔茨海默病(AD)中,这种反应被颠覆并变得有毒,导致r
英文摘要
Microglia are a class of brain immune cells that play an important role in neuroinflammation, a protective response initiated to ward off toxins and pathogens. However, in Alzheimer's disease (AD), this response is subverted and becomes toxic leading to r
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Endoplasmic reticulum stress, Ca2+ permeation pathways and neuronal death.
-
批准号:267030
-
项目类别:Operating Grants
-
资助金额:$53.56万
-
财政年份:2012
-
负责人:Jackson Michael F
-
依托单位:
海外基金