Research on Doppler Three-Dimensional Vector and Capillary Flow Measurement

多普勒三维矢量及毛细管流量测量研究

• 批准号: 9201877
• 负责人: Vernon Newhouse
• 金额: $ 25.3万
• 依托单位: Drexel University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-09-01 至 1997-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9201877&HistoricalAwards=false
• 关键词: Research; Doppler; Three; Dimensional; Vector

This grant will fund the investigation of ultrasound Doppler techniques to estimate blood velocity and detect blood flow related conditions. By manipulating the aperture of an ultrasound transducer, a line type echo spectra will be produced from which the 3-D blood velocity vector, rather than merely the velocity components along and normal to the sound beam axis, will be estimated. Capillary blood flow and perfusion also will be measured through the use of ultrasound contrast materials which can be injected into the blood. These contrast agents have a much stronger echo at the second harmonic of the incident radiation than does tissue and therefore the ratio of the capillary blood echo to that of the surrounding tissue will be enhanced. This research is important since it could lead to advances in ultrasound technology, including the improvement of the performance of current transducers and the design of transducers with certain operating features. The research also could enable flow measurements to be made in some locations where conventional systems are ineffective. The contrast studies should enable more effective visualization of the degree of perfusion. These latter studies also should enable the first measurement of capillary flow to be made using ultrasound.

这笔赠款将资助 超声多普勒研究 血液检测技术 速度和检测血流 相关条件。 通过 操纵光圈 超声波换能器，线型 回波频谱将由 三维血流速度 矢量，而不仅仅是 速度分量沿着和 垂直于声束轴， 估计。 毛细血管血流 灌注也将 条件下使用τ 超声造影材料， 可以注射到血液中。 这些造影剂具有 在第二个更强的回声 入射谐波 辐射比组织和 因此， 毛细血管血液回声 周围的组织将被 增强 这项研究很重要，因为它 可能会导致 超声波技术，包括 的提高 电流传感器性能 和换能器的设计， 某些操作特性。 的 研究也可以使流动 在某些情况下进行测量 传统的地方， 制度是无效的。 的 对比研究应该能够使更多的 有效的可视化 灌注程度。 这些后者 研究还应使 毛细管首次测量 使用超声波进行流动。