The Function of Protein Kinase NEK10 in tumour suppression

蛋白激酶NEK10在肿瘤抑制中的作用

• 批准号: 433063
• 负责人: Stambolic Vuk
• 金额: $ 89.17万
• 依托单位: Princess Margaret Cancer Centre (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-10-01 至 2025-10-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=433063&lang=en
• 关键词: Breast Cancer; Broad Cancer Spectrum; Cancer; Direct Phosphorylation; Genotoxic Agents Sensitivity; Loss Or Gain Of Function; Nek10; P53; Patient Stratification; Protein Kinase

One of the key features of some human cancers is their inability to fix defects in the cancer cell genes. Recent research has identified drugs that specifically take advantage of this property and their clinical development has revolutionized treatment of

一些人类癌症的关键特征之一是它们无法修复癌细胞基因中的缺陷。最近的研究已经确定了专门利用这种特性的药物，并且它们的临床开发已经彻底改变了对糖尿病的治疗。