Investigating signalling changes leading to recurrence in matched primary and recurrent pairs of glioblastoma brain tumour stem cells

研究导致匹配的原发性和复发性胶质母细胞瘤脑肿瘤干细胞对复发的信号变化

• 批准号: 449795
• 负责人: Heemskerk Kyle M
• 金额: $ 1.27万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-12-01 至 2021-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=449795&lang=en
• 关键词: Bioinformatics; Brain Tumour Stem Cells; Glioblastoma; Matched Pairs; Recurrence; Signalling Pathways

Glioblastoma (GBM) is the most common primary brain tumour in adults. High invasiveness, aggressive growth, and recurrence make GBM difficult to treat. Despite the current standard of care, GBM has a median overall survival of a mere 15 months after diagn

胶质母细胞瘤（GBM）是成人中最常见的原发性脑肿瘤。高侵袭性、侵袭性生长和复发使GBM难以治疗。尽管目前的治疗标准，GBM诊断后的中位总生存期仅为15个月。