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Elucidating the Determinants and Mechanisms of Tau Liquid - Liquid Phase Separation In Situ at Multiple Length Scales from µm to Å: Exploring the Role of Membraneless Compartments in Alzheimer's Disease

Elucidating the Determinants and Mechanisms of Tau Liquid - Liquid Phase Separation In Situ at Multiple Length Scales from µm to Å: Exploring the Role of Membraneless Compartments in Alzheimer's Disease
阐明从μm到μm多种长度尺度的Tau液-液相原位分离的决定因素和机制:探索无膜室在阿尔茨海默病中的作用
批准号:
440931
负责人:
Ahmed Rashik
金额:
$10.93万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-12-01 至 2023-12-01

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英文摘要
The build-up of pathological aggregates in the brain comprised of the tau protein is a clinical hallmark of Alzheimer's disease (AD). The progression of AD is closely associated with the spreading of tau aggregates i.e. neurofibrillary tangles (NFTs), thr
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Catechins as Adjuvants in the Treatment of Alzheimer's Disease: Enhancing the Response of Microglia to Amyloid Beta
  • 批准号:
    383278
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $7.65万
  • 财政年份:
    2017
  • 负责人:
    Ahmed Rashik
  • 依托单位:
Probing the Interactions between (-) Epigallo-3-catechin Gallate & Amyloid Beta Assemblies in Alzheimer's Disease
  • 批准号:
    367025
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2016
  • 负责人:
    Ahmed Rashik
  • 依托单位:
海外基金