Environmental Control of Photochemical Reactions and Its Application

附着的光化学和生物物理后果 反应性发色团的亲水性尾部的两亲性 分子将被研究。该计划的主旨将 是为了定义微观异质结构的结构特征， 控制最终反应过程的系统。的 待研究的反应性基团包括苯乙烯基和芪 部分。将使用双功能磷脂， 以提供具有空间精确性的分子种类， 几何学这些几何结构将反应性官能团 在反应如环加成的有利位置。 反应性基团如芪类之间的相互作用， 苯乙烯和多烯将在稀，混合， 纯分散体，试图分离分子间和 分子内过程 %%% 有机动力学计划的这笔赠款支持 大卫·惠顿教授在牛津大学的持续工作 罗切斯特。这些研究将致力于建立一个 更好地了解控制化学物质的因素 非均相体系中的反应。系统将 研究了具有亲水性和亲水性的独特分子， （被水吸引）和疏水（被水排斥） 特性.通过引入反应性化学基团， 作为这些分子的一个组成部分， 可以产生多种反应， 否则就不会发生。对医学和 材料科学的领域很多。

The photochemical and photophysical consequences of attaching reactive chromophores to the hydrohpobic tail of amphiphilic molecules will be investigated. The thrust of the program will be to define the structural features of the microheterogeneous systems which dictate the resultant reaction processes. The reactive groups to be investigated include styryl and stilbene moieties. Bifunctional phospholipids will be utilized in order to provide molecular species which have spatially exact geometries. These geometries place reactive functional groups in favorable positions for reactions such as cycloadditions. Interactions between reactive groups such as stilbenes, styrenes, and polyenes will be studied in dilute, mixed, and pure dispersions in an attempt to separate intermolecular and intramolecular processes. %%% This grant from the Organic Dynamics Program supports the continuing work of Professor David Whitten at the University of Rochester. The studies will be directed to establishing a better understanding of the factors which control chemical reactions in heterogeneous systems. The systems to be investigated are unique molecules which have both hydrophilic (attracted to water) and hydrophobic (repelled by water) properties. By incorporating reactive chemical groups that are responsive to light as an integral part of these molecules, it is possible to produce a variety of reactions which might otherwise fail to occur. Implications for the medical and materials areas of science are numerous.