Defining the role of proteolysis in genital tract infections: from pathways to novel enzymes

定义蛋白水解在生殖道感染中的作用：从途径到新型酶

• 批准号: 448211
• 负责人: Sycuro Laura K
• 金额: $ 21.86万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-04-01 至 2024-04-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=448211&lang=en
• 关键词: Bacterial Virulence Activities; Genital Tract Infection; Metagenomics; Metaproteomics; Proteases; Vaginal Microbiome

Lay Abstract: The vaginal microbiome is typically dominated by a few species of lactobacilli that play an important role in preventing infections. However, in up to 30% of women, the vaginal microbiota is unbalanced and more permissive to the growth of a

摘要：阴道微生物群通常由少数几种在预防感染中起重要作用的乳杆菌主导。然而，在高达30%的女性中，阴道微生物区系不平衡，更容易生长