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In vivo quantification of tau aggregates as a measure of disease progression in Alzheimer's disease spectrum

In vivo quantification of tau aggregates as a measure of disease progression in Alzheimer's disease spectrum
tau 聚集体的体内定量作为阿尔茨海默病谱系疾病进展的衡量标准
批准号：
448418
负责人：
Rosa-Neto Pedro
金额：
$7.29万
依托单位：
CIUSSS de l'Ouest-de-l'Ile-de-Montral-Douglas Hospital
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-04-01 至 2022-04-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=448418&lang=en
关键词：
Alzheimer'S Disease Amyloid Imaging Agents Biomarkers Imaging Pet Amyloid Plasma Biomarkers Tau Imaging Agents

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英文摘要
The major deliverable of this project is the 30-month follow up, large-scale, biomarker study describing tau progression using a second-generation tau imaging agent, CSF and plasma measures of p-tau-181 and the modulation of brain amyloid on these outcome
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Sex differences in brain tau aggregates.
In vivo quantification of tau aggregates as a measure of disease progression in Alzheimer's disease spectrum
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Interactions between pathophysiological processes as drivers of clinical progression in Alzheimer's disease
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