Analytical Biosensors

分析生物传感器

• 批准号: 9216304
• 负责人: Garry Rechnitz
• 金额: $ 80万
• 依托单位: University of Hawaii
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-03-15 至 2000-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9216304&HistoricalAwards=false
• 关键词: Analytical; Biosensors

This project is in the general area of analytical and surface chemistry and in the subfield of biosensors. During the tenure of this three-year continuing grant, Professor Rechnitz and his students will continue the development of tissue based biosensors using plant and animal tissue materials as molecular recognition elements in conjunction with a variety of transducers. This research, which was begun under NSF grant CHE-8921156, will focus on two novel initiatives. In the first, genetically modified plant tissue materials will be used in order to achieve improved sensor stability and to extend the range of possible analytes. In the second, biomagnetic current probes will be introduced as transducers in the design of neuronal biosensors. It is expected that such probes could function as non-invasive transducers and thereby improve the useful lifetimes of chemoreceptor based biosensors. %%% This research is aimed at overcoming some of the major technical problems encountered in biosensor research and, more importantly, to introduce and provide conceptual advances for the future development of analytical biosensors.

该项目属于分析和表面化学的一般领域，以及生物传感器的子领域。在这项为期三年的持续资助期间，雷奇尼茨教授和他的学生将继续开发基于组织的生物传感器，使用植物和动物组织材料作为分子识别元件，并结合各种传感器。这项研究是在美国国家科学基金会的CHE-8921156拨款下开始的，将重点放在两个新的倡议上。首先，将使用转基因植物组织材料，以实现更好的传感器稳定性，并扩大可能的分析范围。在第二章中，我们将在神经元生物传感器的设计中引入生物磁性电流探头作为传感器。这类探针有望作为非侵入性传感器发挥作用，从而延长化学感受器生物传感器的使用寿命。这项研究旨在克服生物传感器研究中遇到的一些主要技术问题，更重要的是，为分析生物传感器的未来发展介绍和提供概念上的进展。