Analytical Biosensors

这个项目属于分析化学和表面化学的一般领域以及生物传感器的子领域。在这项为期三年的持续资助期间，Rechnitz教授和他的学生将继续开发基于组织的生物传感器，使用植物和动物组织材料作为分子识别元件，并结合各种传感器。这项研究由美国国家科学基金会（NSF）资助CHE-8921156开始，将重点关注两个新的倡议。首先，将使用转基因植物组织材料，以提高传感器的稳定性，并扩大可能分析物的范围。第二部分，将引入生物磁电流探针作为神经生物传感器设计中的换能器。预计这种探针可以作为非侵入性传感器，从而提高基于化学受体的生物传感器的使用寿命。本研究旨在克服生物传感器研究中遇到的一些主要技术问题，更重要的是，为分析生物传感器的未来发展介绍和提供概念上的进步。

This project is in the general area of analytical and surface chemistry and in the subfield of biosensors. During the tenure of this three-year continuing grant, Professor Rechnitz and his students will continue the development of tissue based biosensors using plant and animal tissue materials as molecular recognition elements in conjunction with a variety of transducers. This research, which was begun under NSF grant CHE-8921156, will focus on two novel initiatives. In the first, genetically modified plant tissue materials will be used in order to achieve improved sensor stability and to extend the range of possible analytes. In the second, biomagnetic current probes will be introduced as transducers in the design of neuronal biosensors. It is expected that such probes could function as non-invasive transducers and thereby improve the useful lifetimes of chemoreceptor based biosensors. %%% This research is aimed at overcoming some of the major technical problems encountered in biosensor research and, more importantly, to introduce and provide conceptual advances for the future development of analytical biosensors.