Molecular and Functional Genomic Characterization of G-quadruplex in Cancers with the Alternate Lengthening of Telomere (ALT) Mechanism
Molecular and Functional Genomic Characterization of G-quadruplex in Cancers with the Alternate Lengthening of Telomere (ALT) Mechanism
批准号:
451090
负责人:
Wong Judy M
金额:
$69.11万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01
中文摘要
根据保守估计,约10%的人类癌症采用端粒交替延长(ALT)机制作为端粒维持策略,超过20000例新发癌症病例和8000例死亡可归因于
英文摘要
Based on the conservative estimate that ~10 percent of human cancers employ the Alternate Lengthening of Telomere (ALT) mechanism as a telomere maintenance strategy, more than twenty thousand new cancer cases and eight thousand deaths can be attributed to
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