In Situ NMR of Catalytic Reactions

这个研究项目，在分析和表面化学计划中，将开发使用原位核磁共振波谱来研究催化反应。将进行仪器开发，以允许在典型催化系统的高温高压条件下使用核磁共振。该方法将用于对沸石材料的催化化学进行系统研究。此外，还将尝试使用这些方法对酶催化机制进行初步研究。详细了解催化反应的机理对于许多重要的技术，包括商品化工生产和精细化工合成是必不可少的。从核磁共振方法中获得的化学信息可以提供这种理解。该研究项目将开发能够在催化研究中使用NMR的仪器，并将系统地将这些方法应用于重要类别的催化反应。

This research project, in the Analytical and Surface Chemistry Program, will develop the use of in situ NMR spectroscopy for the study of catalytic reactions. Instrumental development will be undertaken to allow the use of NMR under the high temperature and pressure conditions of typical catalytic systems. This approach will be used to carry out a systematic investigation of catalytic chemistry of zeolite materials. In addition, preliminary studies of mechanisms of enzymatic catalysis will be attempted using these methods. %%% A detailed understanding of the mechanisms of catalytic reactions is essential for a number of important technologies, including commodity chemical production and fine chemical synthesis. The chemical information which is available from NMR methods can provide this sort of understanding. This research project will develop instrumentation which will enable the use of NMR in catalytic studies, and will systematically apply these methods to important classes of catalytic reaction.