Regulation of anti-tumor T cell responses by Hippo pathway kinase Mst1

Hippo 通路激酶 Mst1 调节抗肿瘤 T 细胞反应

• 批准号: 458663
• 负责人: Bouchard Antoine
• 金额: $ 7.65万
• 依托单位: Institut de recherches cliniques de Montral
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-11-01 至 2024-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=458663&lang=en
• 关键词: Anti-Tumor T Cell Immunity; Cd8 T Stem-Cell Memory (Tscm); Flow Cytometry And Phosphoflow; Hippo Signaling; Immune Checkpoint Blockade; Immunotherapy; Melanoma Tumor Transplantation Model; Single-Cell Rna Sequencing; T Regulatory Cells (Tregs); Wnt Signal

Upon failure of standard cancer treatments such as radiotherapy and chemotherapy, alternative treatments are essential to cure cancer. Cancer immunotherapy, which is based on increasing the ability of the immune system to fight cancer, has become a promis

在放疗和化疗等标准癌症治疗失败后，替代治疗对于治愈癌症至关重要。以增强免疫系统对抗癌症的能力为基础的癌症免疫疗法已经成为一种前景