Modeling the Chemical Activity of Hydrophobic Organic Com- pounds in Water in the Presence of Co-Solutes

9223656 Jafvert这是一个支持研究的奖项，其目的是确定选定疏水有机化合物的水溶液浓度，其溶解度因存在中等分子量的特定共溶质而增强。预计研究将阐明增强作用的机制，并评估这一特征对选定研究的疏水化合物的流动性和命运的环境影响。这位研究人员计划在他的研究中使用荧光猝灭方法来推断所选疏水有机化合物的溶解度极限及其以下的机理信息。他希望建立描述导致溶解度的过程的机械论和半经验模型，确定与这些模型相关的常数，并通过进行实验室实验来评估模型的质量。这项工作的结果有望增加我们对控制一类溶解度有限的有机化学品在水中的移动和命运的过程的理解，当它们受到提高其溶解度的环境条件的影响时。这一加深的理解可用于评估和模拟水生沉积物中所含疏水危险化学品的影响，作为物理、化学和生物修复过程的一个步骤设计。

9223656 Jafvert This is an award to support research, the objective of which is to determine the aqueous concentrations of select hydrophobic organic compounds, solubility of is enhanced by the presence of specific co-solutes of intermediate molecular weight. Research is expected to elucidate the mechanisms of enhancement and lead to an assessment of the environmental impact this characteristic has on the mobility and fate of the hydrophobic compounds selected for study. The investigator plans on using fluorescence quenching methods in his research to infer mechanistic information at and below the solubility limits for the selected hydrophobic organic compounds. He expects to formulate mechanistic and semi-empirical models that characterize the processes leading to solubility, determine the constants associated with these models and evaluate the quality of the models by conducting laboratory experiments. Results of this work are expected to increase our understanding of processes that control the movement and fate of a class of organic chemicals of limited solubility in water when they are subjected to environmental conditions that enhance their solubility. This enhanced understanding may be applied to assessing and modeling the impacts of hydrophobic hazardous chemicals contained in aquatic sediments as a step design of physical, chemical and biological remediation processes.