Identification and characterization of echinocandin potentiators to combat drug-resistant Candida species.

对抗耐药念珠菌的棘白菌素增效剂的鉴定和表征。

• 批准号: 466683
• 负责人: Fallah Sara
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-12-01 至 2022-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466683&lang=en
• 关键词: Anti-Fungal Drug Discovery; Anti-Fungal Resistance; Chemical Screening; Combination Therapy; Drug Enhancers; Echinocandins; Fungal Infections; Fungal Pathogens; Infectious Disease; Microbiology

Although largely overlooked, fungi cause deadly systemic infections in a growing population of immunocompromised patients that encompass high-dose corticosteroids users, solid organ transplant recipients, and those infected with HIV. Candida albicans is a

尽管真菌在很大程度上被忽视，但它在越来越多的免疫功能低下患者中引起致命的全身性感染，这些患者包括高剂量皮质类固醇使用者、实体器官移植接受者和艾滋病毒感染者。白色念珠菌是一种