Ontogeny of T cell control by BTLA and PD-1

BTLA 和 PD-1 控制 T 细胞的个体发育

• 批准号: 461624
• 负责人: Anderson Colin C
• 金额: $ 65.2万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-03-01 至 2027-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=461624&lang=en
• 关键词: Autoimmune Disease; Immunologic Tolerance

It is being increasingly found that factors that occur very early in life can promote the generation of disease later in life, and this is also true for autoimmune diseases. Our research focuses on two molecules, receptors known as PD-1 and BTLA, present

人们越来越多地发现，生命早期发生的因素可以促进生命后期疾病的产生，这对于自身免疫性疾病也是如此。我们的研究集中在两种分子上，即PD-1和BTLA受体，