High resolution, single-cell characterization of molecular and cellular networks, within and across brain regions, related to sex-associated differences in major depressive disorder.

大脑区域内和跨大脑区域的分子和细胞网络的高分辨率、单细胞特征，与重度抑郁症的性别相关差异相关。

• 批准号: 461366
• 负责人: Nagy Corina
• 金额: $ 63.53万
• 依托单位: CIUSSS de l'Ouest-de-l'Ile-de-Montral-Douglas Hospital
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-03-01 至 2027-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=461366&lang=en
• 关键词: Depression; Functional Genomics; Human Research; Neurobiology; Postmortem Brain; Psychiatric Phenotype; Sex-Based Differences; Single-Cell

One in 5 Canadians and almost 350 million people worldwide suffer from major depressive disorder (MDD). Depression has devastating consequences on human health, affecting all facets of life. Though treatment options exist, there remains a barrier to the p

五分之一的加拿大人和全球近3.5亿人患有严重抑郁障碍(MDD)。抑郁症对人类健康具有毁灭性的后果，影响到生活的方方面面。尽管有治疗方法可供选择，但仍存在障碍。