Presidential Faculty Fellow

青木博士已被选为30个著名的NSF之一， 总统学院奖学金的基础上，她的杰出奖 研究成就。 在本次获奖期间，青木博士 将使用电子显微镜免疫细胞化学来鉴定 化学上特定的轴突或生长锥， 完整皮质组织内的递质受体。 出生时 大脑皮层中突触的密度不超过 成年人的水平，目前还不知道 皮质内化学上指定的突触的发育。 的 早期去甲肾上腺素能和兴奋性突触的成熟 生命对于理解 是大脑皮层可塑性的基础 去甲肾上腺素的重要性 大脑皮层的可塑性反映在一个新的工作假设中， 支持的结果是，皮质可塑性是由 利用两种儿茶酚胺的兴奋性突触的双重调节 和乙酰胆碱。

Dr. Aoki has been selected to receive one of 30 prestigious NSF Presidential Faculty Fellowship awards based upon her outstanding research accomplishments. During the period of this award, Dr. Aoki will be using electron microscopic immunocytochemistry to identify chemically specified axons or growth cones in relation to transmitter receptors within intact cortical tissue. At birth, the density of synapses in the cerebral cortex is no more than 10% of the adult level, and nothing is presently known about the development of chemically specified synapses within cortex. The maturation of noradrenergic and excitatory synapses during early life is particularly important for understanding the mechanisms that underlie cortical plasticity. The importance of noradrenaline in cortical plasticity is reflected in a new working hypothesis supported by results that cortical plasticity is dictated by the dual modulation of excitatory synapses utilizing both catecholamines and acetylcholine.