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Establishing the role of ZMYM2 in mediating transcriptional silencing and DNA methylation during mammalian embryonic development

Establishing the role of ZMYM2 in mediating transcriptional silencing and DNA methylation during mammalian embryonic development
确定 ZMYM2 在哺乳动物胚胎发育过程中介导转录沉默和 DNA 甲基化中的作用
批准号:
468458
负责人:
Pastor William A
金额:
$62.42万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-09-01 至 2027-09-01

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中文摘要
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英文摘要
During development, genes must be activated or silenced at precise times and places in order for an embryo to make all of the right tissues and survive. This is done in part by DNA methylation, which is a chemical modification of DNA critical for "silenci
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Role of ZMYM2 in guiding de novo methylation in mammalian development
  • 批准号:
    464581
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Pastor William A
  • 依托单位:
Transcriptional Regulation of Human Trophoblast Development
  • 批准号:
    401854
  • 项目类别:
    Operating Grants
  • 资助金额:
    $61.3万
  • 财政年份:
    2019
  • 负责人:
    Pastor William A
  • 依托单位:
海外基金