Optogenetic and pharmacological characterization of leader and follower beta-cell coordination and its impact into the islet´s calcium dynamics.

领导者和追随者 β 细胞协调的光遗传学和药理学特征及其对胰岛钙动力学的影响。

• 批准号: 472014
• 负责人: Delgadillo Silva Luis F
• 金额: $ 6.56万
• 依托单位: Centre hospitalier de l'Universit de Montral (CHUM)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-10-01 至 2024-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=472014&lang=en
• 关键词: Calcium Imaging; Calcium Mobilization; Cell Biology; Connexins; Diabetes; Influx Of Calcium; Insulin; Optogenetics; Serca2; Tissue Coordination

The coordination of activity is present across nature, from the harmonized flight of starlings to the coordinated activity of large areas of the human brain to generate ideas. Healthy pancreatic Beta-cells coordinate their function to keep the right gluco

从欧椋鸟的协调飞行到人类大脑产生想法的大面积协调活动，这种活动的协调存在于整个自然界。健康的胰腺β细胞协调它们的功能来保持正确的葡萄糖水平