Steric Modulation of Electronic Effects

电子效应的空间调制

• 批准号: 9302747
• 负责人: Joseph Lambert
• 金额: $ 56.56万
• 依托单位: Northwestern University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-04-15 至 1998-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9302747&HistoricalAwards=false
• 关键词: Steric; Modulation; Electronic; Effects

This grant from the Organic Dynamics Program supports the continuing work of Professor Joseph B. Lambert at Northwestern University, who will study stereoelectronic aspects of reactive intermediates. One focal point is to determine how electronic effects are propagated through sigma bonds. Targets are to evaluate the zeta effect of stannylenium ions, the mechanism of the beta- silicon effect, and a search for the beta-phosphonate effect in carbocation formation. The second focal point is to obtain new formulations of solvents and anions to produce free silyl, germyl, and stannyl cations. The third topic concerns conformations of flexible molecules in the solid state, which is footed on five- membered rings and the use of a cultivated solid state NMR spectroscopic technique. %%% The results from Professor Joseph B. Lambert's studies on reactive intermediates will contribute to our understanding on how electronic effects are propagated through bonds. His research is focussed largely on silyl and stannyl cations. Their isolation is also sought to verify their existence as intermediates. These mechanistic studies have the potential to translate in a broad spectrum of synthetic applications. Novel conformational studies on cyclopentanes will be conducted that will provide information that is relevant in the area of molecular dynamics.//

有机动力学计划的这笔赠款支持 约瑟夫B教授的继续工作。西北大学的兰伯特 大学，谁将研究立体电子方面的反应 中间体的一个焦点是确定电子 效应通过sigma键传播。目标是评估 锡离子的zeta效应，β- 硅的影响，并寻找β-膦酸盐的影响， 碳正离子形成第二个重点是获得新的 溶剂和阴离子的配制以产生游离甲硅烷基，甲锗烷基， 和甲锡烷基阳离子。第三个主题涉及构象 固态的柔性分子，它的基础是五个- 和培养的固态NMR的用途 光谱技术 %%% 约瑟夫教授B的结果。Lambert对反应性的研究 中间体将有助于我们理解 电子效应通过键传播。他的研究是 主要集中在甲硅烷基和甲锡烷基阳离子上。他们的孤立是 还试图验证它们作为中间体的存在。这些 机械研究有可能转化为广泛的 合成应用的范围。新的构象研究 环戊烷将进行，将提供信息， 在分子动力学领域是相关的。