Effect of IRF1 Ablation in Different Leukocyte Populations on Susceptibility to Mycobacteria
Effect of IRF1 Ablation in Different Leukocyte Populations on Susceptibility to Mycobacteria
批准号:
500270
负责人:
Azzuolo Alessia
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-12-01 至 2023-12-01
中文摘要
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英文摘要
IRF1 has been identified as a major mediator of antiviral responses by amplifying effects of type I and type II interferons. Inborn errors of IFN-g pathways lead to impaired immune function and cause Mendelian Susceptibility to Mycobacterial Diseased (MSM
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