Midgut Hormone: A Newly Discovered Endocrine Link Between Diet and the Neuroendocrine System in Phormia Regina (Meigen)

小行星9306650 黑腹果蝇（Phormia regina）是一种常见的黑腹果蝇，已被广泛用于研究从摄食行为到卵发育的各个方面的生物学。 众所周知，许多成年昆虫在产卵之前需要蛋白质餐。然而，这是如何发生的，或者更恰当地说，“营养和卵子发育之间的联系是什么”，这一点还有待理解。“该小组以前的研究表明，有一种中肠激素提供了这种联系。 目前的研究旨在纯化和鉴定这种激素。 一旦这样做了，将开发一种测试，允许确定这种激素在昆虫的血液中的水平后，蛋白质餐。 最后，PI将使用另一种测试来确定这种激素的产生及其作用部位。这项研究的主要意义在于，这种新的激素可能提供一种新的干扰和阻止卵子发育的新方法。 这种技术应该作为控制其他昆虫卵发育的示范模型。***

9306650 Yin Phormia regina, the common black blowfly, has been used extensively to study various aspects of biology from feeding behavior to egg development. It is common knowledge that many adult insects need a protein meal before they can develop eggs. What remains to be understood, however, is how this happens or, more aptly put, "What is the link between nutrition and egg development." Previous research by the group has shown that there is a midgut hormone that provides this link. The current study is designed to purify and identify this hormone. Once this has been done, a test will be developed permitting the determination of the levels of this hormone in the insect's blood following a protein meal. Finally, the PI will use another test to determine where this hormone is produced and its site of action. The major significance of this research is that this new hormone may provide a new and novel way to interfere with and prevent egg development. Such a technique should serve as an exemplar model for controlling egg development in other insects. ***