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Developmental cellular origins of pediatric medulloblastoma

Developmental cellular origins of pediatric medulloblastoma
儿童髓母细胞瘤的发育细胞起源
批准号:
488211
负责人:
Pai Shraddha
金额:
$4.55万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-02-01 至 2024-02-01

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中文摘要
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英文摘要
Medulloblastoma is a common, malignant childhood brain cancer in sore need of molecular therapies. These tumours are believed to arise before birth and are diverse at the molecular level, making it hard to design a “one-size-fits-all” therapy. We will use
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Developmental epigenetic origins of Group 3 and 4 medulloblastoma
Mapping epigenetic signatures of aberrant gene splicing in aging mouse and human brain
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