Glial-Neuronal Interactions in the Superior Cervical Ganglion
Glial-Neuronal Interactions in the Superior Cervical Ganglion
批准号:
9310511
负责人:
Alison Hall
金额:
$12.26万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1993
资助国家:
美国
项目状态:
已结题
起止时间:
1993-09-01 至 1995-08-31
中文摘要
9310511霍尔神经系统由两种主要细胞类型组成,神经元和神经胶质细胞。神经胶质细胞有许多重要的作用,使神经元能够发挥作用。不同类型的胶质细胞具有不同的功能,神经系统的不同部位需要不同的神经胶质细胞。人们对神经系统发育过程中不同类型的神经胶质细胞是如何产生的知之甚少。这项研究将确定神经元在发育过程中如何改变神经胶质细胞,并将建立神经和神经节两种类型神经胶质细胞之间的异同。需要检验的假设是,神经胶质细胞前体在神经元因子的作用下分裂并成熟为这两种类型的神经胶质细胞中的任何一种。一种细胞培养系统已经开发出来,这将使这一假说得到验证。来自这些研究的信息将有助于更好地理解细胞之间的相互作用如何影响正常神经系统的发育。*9310511霍尔神经系统由两种主要细胞类型组成,神经元和胶质细胞。神经胶质细胞有许多重要的作用T Y!!F(Times New Roman Symbol&;Arial“h C??Hall William Proctor,IBN William Proctor,IBN
英文摘要
9310511 Hall The nervous system is composed of two major cell types, neurons and glia. Glial cells have many important roles that allow the neurons to function. Different types of glial cells have different functions and are needed in different parts of the nervous system. Little is known about how the different glial cell types arise during development of the nervous system. This study will define how neurons alter glial cells during the development, and will establish the similarities and differences between two types of glial cells, those of nerves and those of ganglia. The hypothesis to be tested is that glial cell precursors divide and mature into either of these two types of glia in response to factors from the neurons. A cell culture system has been developed that will allow this hypothesis to be tested. Information from these studies will lead to a greater understanding of how cell-cell interactions influence development in the normal nervous system. *** 9310511 Hall The nervous system is composed of two major cell types, neurons and glia. Glial cells have many important roles T Y ! ! F ( Times New Roman Symbol & Arial " h C ? ? hall William Proctor, IBN William Proctor, IBN
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海外基金
mt DNA/AIM2 inflammasome/ neuronal pyroptosis途径参与创伤性颅脑损伤后认知功能障碍发生的作用机制研究
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批准号:
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项目类别:省市级项目
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资助金额:10.0万元
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批准年份:2022
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负责人:盛江涛
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依托单位: