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Impact of exposure to hyperglycemia during pregnancy on offspring airway smooth muscle contractility and the activity of RhoA

Impact of exposure to hyperglycemia during pregnancy on offspring airway smooth muscle contractility and the activity of RhoA
妊娠期间暴露于高血糖对后代气道平滑肌收缩力和 RhoA 活性的影响
批准号：
488936
负责人：
Pascoe Christopher D
金额：
$57.12万
依托单位：
University of Manitoba
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2023
资助国家：
加拿大
项目状态：
未结题
起止时间：
2023-09-01 至 2028-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=488936&lang=en
关键词：
Airway Smooth Muscle Animal Model Asthma Developmental Origins Gestational Diabetes Rhoa Stem Cell

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中文摘要
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英文摘要
People who have diabetes while they are pregnant are more likely to have children at risk for developing asthma later in life. Asthma causes the airways of the lung to become twitchy and narrow too much. Like breathing through a straw, these smaller airwa
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Impact of maternal hyperglycemia on offspring airway smooth muscle contractility and the activity of RhoA.
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    477336
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    2022
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    University of Manitoba
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Assessing the impact of in utero exposure to high fat diet and gestational diabetes on allergen sensitivity in mouse offspring
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