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Aging, CMV and Alzheimer disease: could immunosenescence be a common pathway?

Aging, CMV and Alzheimer disease: could immunosenescence be a common pathway?
衰老、CMV 和阿尔茨海默病:免疫衰老可能是一种常见途径吗?
批准号:
176111
负责人:
Fulop Tams
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-09-01 至 2009-09-01

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中文摘要
翻译
阿尔茨海默病(AD)是最常见的痴呆症。其病理特征包括严重的神经元丢失,神经元内神经原纤维缠结的存在和β淀粉样蛋白(A)的沉积。这种疾病,虽然在表型上是罕见的
英文摘要
Alzheimer disease (AD) is the most common form of dementia. Its pathological hallmarks include profound neuronal loss, presence of intraneuronal neurofibrillary tangles and deposition of beta amyloid protein (A). This disease, although phenotypically mani
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Immune signatures predicting development and progression of Alzheimer Disease: impact of immunosenescence and Cytomegalovirus infection.
How do catastrophic events by modulating the immune response lead to frailty?
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