Directed Reactions of Indenyl-Metal Complexes

9315999傅本奖为傅博士化学博士后科研奖励的启动经费增量。研究的重点是利用独立金属配合物来指导催化过程。具体来说，金属结合的独立基配体的环滑移将被利用来打开金属体系上的配位位点，为催化提供必要的配位不饱和反应中间体。该机制的一个重要特征是由于过渡态的高水平组织而增强了反应的立体控制。初步研究将探索独立铑配合物在催化烯烃氢化、硼氢化和氢甲酰化中的作用。这项定向催化反应的研究将为反应性提供基本的见解，并为合成有机化学提供新的方法。＊＊＊

9315999 Fu This award is the starter grant increment of Dr. Fu's Postdoctoral Research Fellowships in Chemistry award. The focus of the research deals with the use of indenyl-metal complexes to direct catalytic processes. Specifically, ring slippage of the metal-bound indenyl ligand will be exploited to open up coordination sites on metal systems to provide the necessary coordinatively-unsaturated reactive intermediates for catalysis. An important feature of this mechanism is enhanced stereocontrol of the reaction due to the high level of organization in the transition state. Initial studies will explore indenylrhodium complexes in catalytic olefin hydrogenation, hydroboration and hydroformylation. %%% This research on directed catalytic reactions will provide fundamental insights into reactivity as well as new methods for synthetic organic chemistry. ***