Investigating the role of Nrf2 and HNF4alpha in in utero high fat diet-induced nonalcoholic fatty liver disease.

研究 Nrf2 和 HNF4α 在子宫内高脂肪饮食诱导的非酒精性脂肪肝中的作用。

• 批准号: 203226
• 负责人: Renaud Helen J
• 金额: $ 10.93万
• 依托单位: Kansas University Medical Center (Kansas)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-02-01 至 2013-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=203226&lang=en
• 关键词: Fetal Origins Of Nonalcoholic Liver Disease; Maternal High Fat Diet Related Fetal Epigenetic Changes; Role Of Transcription Factors In Fetal Programming

Nonalcoholic fatty liver disease (NAFLD) is a serious liver condition because severe cases can lead to end-stage liver disease, hepatocellular carcinoma, and liver-related mortality. NAFLD is the most common cause of liver disease in adults and children a

非酒精性脂肪性肝病（NAFLD）是一种严重的肝脏疾病，因为严重病例可导致终末期肝病，肝细胞癌和肝脏相关死亡率。NAFLD是成人和儿童肝脏疾病的最常见原因，