Bioremediation of Diaryl Ethers by Pseudomonas strain POB 310

9318788 Dwyer这是一个为研究提供支持的奖项，其目的是确定已被证明能够降解土壤有机污染物的细菌可用于现场规模土壤去污的条件。 该研究人员计划研究的目标有机化合物是二芳基醚，这类化合物包括二恶英，具有重大污染意义的物质。 研究人员计划使用的生物体，假产碱假单胞菌，已被发现可以降解二芳基醚，这一特性可归因于其含有切割这些化合物醚键的酶的基因。 这项研究的结果预计将包括该生物体及其酶的底物范围，适用于现场规模操作的条件及其降解目标物质的基因的稳定性。 这项研究预计将提供指导的条件下，微生物可能会被评估，为他们的使用， 土壤的净化，并提供系统的工程设计，以消除土壤中的目标污染物的基础。 ***

9318788 Dwyer This is an award to provide support for research, the objective of which is to determine conditions under which bacteria that have been shown to be capable of degrading organic contaminants of soil can be utilized in field-scale decontamination of soil. The target organic compounds this investigator plans to work on are diaryl ethers, compounds that as a class include the dioxins, substances of great pollutional significance. The organism the investigator plans to use, Pseudomonas pseudoalcaligenes, has been found to degrade diaryl ethers, a property attributable to its containing genes for enzymes that cleave these compound's ether bond. Results of this research are expected to include the substrate range for this organism and its enzymes, the conditions that are appropriate for its use in field-scale operations and the stability of its genes for degradation of the target substances. This research is expected to provide guidance for the conditions under which microorganisms may be evaluated for their use in decontamination of soils and provide the basis for engineering design of systems to remove the target contaminants from soil. ***