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Investigations of the drug and organic anion transporter ABCC4

Investigations of the drug and organic anion transporter ABCC4
药物和有机阴离子转运蛋白 ABCC4 的研究
批准号：
200903
负责人：
Cole Susan P
金额：
$48.34万
依托单位：
Queen's University (Kingston, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-03-01 至 2015-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=200903&lang=en
关键词：
Cancer Chemotherapy Drug And Organic Anion Transport Drug Disposition Gene Regulation Membrane Protein Trafficking Multidrug Resistance Protein

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中文摘要
翻译
有许多因素决定药物的有效性和毒性（不良副作用）。在抗癌药物的情况下，这在很大程度上取决于有多少药物能够到达肿瘤（期望的目标）和多少d
英文摘要
There are many factors that determine both the effectiveness and toxicity (adverse side effects) of drugs. In the case of an anticancer drug, this is largely determined by how much of the drug is able to reach the tumour (desired target) versus how much d
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Investigations of the drug and organic anion transporter, MRP1